Sarilumab Administration in COVID-19 Patients: Literature Review and Considerations

• Egile Nagusiak: Andrea Marino (Egilea), Antonio Munafò (Egilea), Egle Augello (Egilea), Carlo Maria Bellanca (Egilea), Carmelo Bonomo (Egilea), Manuela Ceccarelli (Egilea), Nicolò Musso (Egilea), Giuseppina Cantarella (Egilea), Bruno Cacopardo (Egilea), Renato Bernardini (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Two years have passed since WHO declared a pandemic state for SARS-CoV-2 infection. COVID-19 pathogenesis consists of a first viral phase responsible for early symptoms followed by an inflammatory phase, cytokine-mediated, responsible for late-onset manifestations up to ARDS. The dysregulated immune...