Validation of a [3H]Astemizole Binding Assay in HEK293 Cells Expressing HERG K+ Channels
A radioligand binding assay for the HERG (human ether-a-go-go-related gene) K+ channel was developed to identify compounds which may have inhibitory activity and potential cardiotoxicity. Pharmacological characterization of the [3H]astemizole binding assay for HERG K+ channels was performed using HE...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2004-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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