A Genotype-Phenotype Analysis of Glutathione Peroxidase 4 in Human Atrial Myocardium and Its Association with Postoperative Atrial Fibrillation

• Main Authors: Islam A. Berdaweel (Author), Alexander A. Hart (Author), Andrew J. Jatis (Author), Nathan Karlan (Author), Shahab A. Akhter (Author), Marie E. Gaine (Author), Ryan M. Smith (Author), Ethan J. Anderson (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Heterogeneity in the incidence of postoperative atrial fibrillation (POAF) following heart surgery implies that underlying genetic and/or physiological factors impart a higher risk of this complication to certain patients. Glutathione peroxidase-4 (GPx4) is a vital selenoenzyme responsible for neutr...