Neutrophils Contribute to the Protection Conferred by ArtinM against Intracellular Pathogens: A Study on Leishmania major.

• Main Authors: Rafael Ricci-Azevedo (Author), Aline Ferreira Oliveira (Author), Marina C A V Conrado (Author), Fernanda Caroline Carvalho (Author), Maria Cristina Roque-Barreira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ArtinM, a D-mannose binding lectin from Artocarpus heterophyllus, has immunomodulatory activities through its interaction with N-glycans of immune cells, culminating with the establishment of T helper type 1 (Th1) immunity. This interaction protects mice against intracellular pathogens, including Le...