Identification of immunogenic Salmonella enterica serotype Typhi antigens expressed in chronic biliary carriers of S. Typhi in Kathmandu, Nepal.

• Main Authors: Richelle C Charles (Author), Tania Sultana (Author), Mohammad Murshid Alam (Author), Yanan Yu (Author), Ying Wu-Freeman (Author), Meagan Kelly Bufano (Author), Sean M Rollins (Author), Lillian Tsai (Author), Jason B Harris (Author), Regina C LaRocque (Author), Daniel T Leung (Author), W Abdullah Brooks (Author), Tran Vu Thieu Nga (Author), Sabina Dongol (Author), Buddha Basnyat (Author), Stephen B Calderwood (Author), Jeremy Farrar (Author), Farhana Khanam (Author), John S Gunn (Author), Firdausi Qadri (Author), Stephen Baker (Author), Edward T Ryan (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Salmonella enterica serotype Typhi can colonize and persist in the biliary tract of infected individuals, resulting in a state of asymptomatic chronic carriage. Chronic carriers may act as persistent reservoirs of infection within a community and may introduce infection to susceptible ind...