Alpinia oxyphylla Miq extract reduces cerebral infarction by downregulating JNK-mediated TLR4/T3JAM- and ASK1-related inflammatory signaling in the acute phase of transient focal cerebral ischemia in rats

Abstract Background Post-ischemic inflammation is a crucial component in stroke pathology in the early phase of cerebral ischemia-reperfusion (I/R) injury. Inflammation caused by microglia, astrocytes, and necrotic cells, produces pro-inflammatory mediators and exacerbates cerebral I/R injury. This...

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Main Authors: Chin-Yi Cheng (Author), Su-yin Chiang (Author), Shung-Te Kao (Author), Shang-Chih Huang (Author)
Format: Book
Published: BMC, 2021-08-01T00:00:00Z.
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