In utero particulate matter exposure in association with newborn mitochondrial ND4L10550A>G heteroplasmy and its role in overweight during early childhood

• Main Authors: Charlotte Cosemans (Author), Congrong Wang (Author), Rossella Alfano (Author), Dries S. Martens (Author), Hanne Sleurs (Author), Yinthe Dockx (Author), Kenneth Vanbrabant (Author), Bram G. Janssen (Author), Charlotte Vanpoucke (Author), Wouter Lefebvre (Author), Karen Smeets (Author), Tim S. Nawrot (Author), Michelle Plusquin (Author)
• Format: Book
• Published: BMC, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mitochondria play an important role in the energy metabolism and are susceptible to environmental pollution. Prenatal air pollution exposure has been linked with childhood obesity. Placental mtDNA mutations have been associated with prenatal particulate matter exposure and MT-ND4...