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Discovery of a Novel Natural Allosteric Inhibitor That Targets NDM-1 Against Escherichia coli

At present, the resistance of New Delhi metallo-β-lactamase-1 (NDM-1) to carbapenems and cephalosporins, one of the mechanisms of bacterial resistance against β-lactam antibiotics, poses a threat to human health. In this work, based on the virtual ligand screen method, we found that carnosic acid1 (...

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Bibliografske podrobnosti
Main Authors:	Yanan Yang (Author), Yan Guo (Author), Yonglin Zhou (Author), Yawen Gao (Author), Xiyan Wang (Author), Jianfeng Wang (Author), Xiaodi Niu (Author)
Format:	Knjiga
Izdano:	Frontiers Media S.A., 2020-10-01T00:00:00Z.
Teme:	article
Online dostop:	Connect to this object online.
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