Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activities

Pyridazine scaffolds are considered privileged structures pertaining to its novelty, chemical stability, and synthetic feasibility. In our quest towards the development of novel scaffolds for effective vascular endothelial growth 2 (VEGFR-2) inhibition with antiangiogenic activity, four novel series...

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Hoofdauteurs: Maiy Y. Jaballah (Auteur), Rabah A. T. Serya (Auteur), Nasser Saad (Auteur), Sohair M. Khojah (Auteur), Marawan Ahmed (Auteur), Khaled Barakat (Auteur), Khaled A. M. Abouzid (Auteur)
Formaat: Boek
Gepubliceerd in: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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