Dimethyl fumarate abrogates striatal endoplasmic reticulum stress in experimentally induced late-stage Huntington's disease: Focus on the IRE1α/JNK and PERK/CHOP trajectories

Introduction: Dimethyl fumarate (DMF) is FDA-approved for use in patients with relapsing multiple sclerosis, and it processes neuroprotection in several experimental settings; however, its impact on combating Huntington's disease (HD) remains elusive. This study aimed to explore the role of DMF...

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Hauptverfasser: Lina Y. Hassab (Verfasst von), Samah S. Abbas (Verfasst von), Reham A. Mohammed (Verfasst von), Dalaal M. Abdallah (Verfasst von)
Format: Buch
Veröffentlicht: Frontiers Media S.A., 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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