Restoration of Sarco/Endoplasmic Reticulum Ca2+-ATPase Activity Functions as a Pivotal Therapeutic Target of Anti-Glutamate-Induced Excitotoxicity to Attenuate Endoplasmic Reticulum Ca2+ Depletion

• Asıl Yazarlar: Wen Zhang (Yazar), Fanghua Ye (Yazar), Nan Pang (Yazar), Miriam Kessi (Yazar), Juan Xiong (Yazar), Shimeng Chen (Yazar), Jing Peng (Yazar), Li Yang (Yazar), Fei Yin (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Glutamate-induced excitotoxicity is a pathological basis of many acute/chronic neurodegenerative diseases. Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2b) is a membrane-embedded P-type ATPase pump that manages the translocation of calcium ions (Ca2+) from cytosol into the lumen of the endoplasmic...