miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBPα

• Main Authors: Jia Bi (Author), Xianxin Zeng (Author), Lin Zhao (Author), Qian Wei (Author), Lifeng Yu (Author), Xinnan Wang (Author), Zhaojin Yu (Author), Yaming Cao (Author), Fengping Shan (Author), Minjie Wei (Author)
• Format: Book
• Published: Elsevier, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages can acquire a variety of polarization status and functions: classically activated macrophages (M1 macrophages); alternatively activated macrophages (M2 macrophages). However, the molecular basis of the process is still unclear. Here, this study addresses that microRNA-181a (miR-181a) is...