Luteoloside Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration

• Main Authors: Jialiang Lin (Author), Jiaoxiang Chen (Author), Zengjie Zhang (Author), Tianzhen Xu (Author), Zhenxuan Shao (Author), Xiaobin Wang (Author), Yuanzhe Ding (Author), Naifeng Tian (Author), Haiming Jin (Author), Sunren Sheng (Author), Weiyang Gao (Author), Yan Lin (Author), Xiaolei Zhang (Author), Xiangyang Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intervertebral disk degeneration (IDD) is the major cause of low back pain (LBP), which affects 80% of the world's population. Interleukin 1 beta (IL-1β) is a major inflammatory factor that accelerates disk degeneration, and IL-1β levels increase in degenerative disks. It has recently been repo...