Understanding the molecular mechanisms of human microtia via a pig model of HOXA1 syndrome

• Main Authors: Ruimin Qiao (Author), Yuyong He (Author), Bo Pan (Author), Shijun Xiao (Author), Xufei Zhang (Author), Jing Li (Author), Zhiyan Zhang (Author), Yuan Hong (Author), Yuyun Xing (Author), Jun Ren (Author)
• Format: Book
• Published: The Company of Biologists, 2015-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microtia is a congenital malformation of the outer ears. Although both genetic and environmental components have been implicated in microtia, the genetic causes of this innate disorder are poorly understood. Pigs have naturally occurring diseases comparable to those in humans, providing exceptional...