Concentration-dependent alpha1-Adrenoceptor Antagonism and Inhibition of Neurogenic Smooth Muscle Contraction by Mirabegron in the Human Prostate

• Main Authors: Ru Huang (Author), Yuhan Liu (Author), Anna Ciotkowska (Author), Alexander Tamalunas (Author), Raphaela Waidelich (Author), Frank Strittmatter (Author), Christian G. Stief (Author), Martin Hennenberg (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Mirabegron is available for treatment of storage symptoms in overactive bladder, which may be improved by β3-adrenoceptor-induced bladder smooth muscle relaxation. In addition to storage symptoms, lower urinary tract symptoms in men include obstructive symptoms attributed to benign pro...