Lappaol F regulates the cell cycle by activating CDKN1C/p57 in human colorectal cancer cells

AbstractContext Lappaol F (LAF), a natural lignan from Arctium lappa Linné (Asteraceae), inhibits tumor cell growth in vitro and in vivo. The underlying mechanism involves the suppression of the Yes-associated protein. However, the specific role of LAF in cell cycle regulation remains unknown.Object...

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Main Authors: Rui-Yi Yang (Author), Jia-Yi Tan (Author), Zhe Liu (Author), Xiao-Ling Shen (Author), Ying-Jie Hu (Author)
Formato: Livro
Publicado em: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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