Functional Activation of G-Proteins Coupled With Muscarinic Acetylcholine Receptors in Rat Brain Membranes

• Main Authors: Yuji Odagaki (Author), Masakazu Kinoshita (Author), Ryoichi Toyoshima (Author)
• Formato: Libro
• Publicado: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Abstract.: The functional activation of Gi/o proteins coupled to muscarinic acetylcholine receptors (mAChRs) was investigated with the conventional guanosine-5'-O-(3-[35S]thio)triphosphate ([35S]GTPγS) binding assay in rat brain membranes. The most efficacious stimulation elicited by acetylchol...