Declines in muscle protein synthesis account for short‐term muscle disuse atrophy in humans in the absence of increased muscle protein breakdown

• Main Authors: Matthew S. Brook (Author), Tanner Stokes (Author), Stefan H.M. Gorissen (Author), Joseph J. Bass (Author), Chris McGlory (Author), Jessica Cegielski (Author), Daniel J. Wilkinson (Author), Bethan E. Phillips (Author), Ken Smith (Author), Stuart M. Phillips (Author), Philip J. Atherton (Author)
• Format: Book
• Published: Wiley, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background We determined the short‐term (i.e. 4 days) impacts of disuse atrophy in relation to muscle protein turnover [acute fasted‐fed muscle protein synthesis (MPS)/muscle protein breakdown (MPB) and integrated MPS/estimated MPB]. Methods Healthy men (N = 9, 22 ± 2 years, body mass index...