Critical involvement of lysyl oxidase in seizure-induced neuronal damage through ERK-Alox5-dependent ferroptosis and its therapeutic implications

• Main Authors: Xiaoyuan Mao (Author), Xuan Wang (Author), Mingzhu Jin (Author), Qin Li (Author), Jining Jia (Author), Menghuan Li (Author), Honghao Zhou (Author), Zhaoqian Liu (Author), Weilin Jin (Author), Yanli Zhao (Author), Zhong Luo (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent insights collectively suggest the important roles of lysyl oxidase (LysOX) in the pathological processes of several acute and chronic neurological diseases, but the molecular regulatory mechanisms remain elusive. Herein, we explore the regulatory role of LysOX in the seizure-induced ferroptot...