Intravenously Injected Mesenchymal Stem Cells Penetrate the Brain and Treat Inflammation-Induced Brain Damage and Memory Impairment in Mice

• Main Authors: Olena Lykhmus (Author), Lyudmyla Koval (Author), Larysa Voytenko (Author), Kateryna Uspenska (Author), Serhiy Komisarenko (Author), Olena Deryabina (Author), Nadia Shuvalova (Author), Vitalii Kordium (Author), Alina Ustymenko (Author), Vitalii Kyryk (Author), Maryna Skok (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuroinflammation is regarded as one of the pathogenic factors of Alzheimer disease (AD). Previously, we showed that mice regularly injected with bacterial lipopolysaccharide (LPS) possessed the AD-like symptoms like episodic memory decline, elevated amounts of amyloid beta (Aβ) peptide (1-42), and...