Icariin regulates stem cell migration for endogenous repair of intervertebral disc degeneration by increasing the expression of chemotactic cytokines

• Main Authors: Zhaofei Zhang (Author), Fengwei Qin (Author), Yonghui Feng (Author), Sineng Zhang (Author), Chunliang Xie (Author), He Huang (Author), Chaohui Sang (Author), Shaoyu Hu (Author), Feng Jiao (Author), Jie Jiang (Author), Yi Qin (Author)
• Format: Book
• Published: BMC, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Icariin (ICA) can promote the migration and bone formation of bone marrow mesenchymal stem cells. This study explored a potential role of ICA in recruiting stem cell niches (SCNs) within the intervertebral disc region (ISN)-derived stem cells (ISN-SCs) to treat intervertebral dis...