Small Molecules Greatly Improve Conversion of Human-Induced Pluripotent Stem Cells to the Neuronal Lineage

• Principais autores: Sally K. Mak (Autor), Y. Anne Huang (Autor), Shifteh Iranmanesh (Autor), Malini Vangipuram (Autor), Ramya Sundararajan (Autor), Loan Nguyen (Autor), J. William Langston (Autor), Birgitt Schüle (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2012-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Efficient in vitro differentiation into specific cell types is more important than ever after the breakthrough in nuclear reprogramming of somatic cells and its potential for disease modeling and drug screening. Key success factors for neuronal differentiation are the yield of desired neuronal marke...