Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells

• Main Authors: Mostafa Kiamehr (Author), Leena E. Viiri (Author), Terhi Vihervaara (Author), Kaisa M. Koistinen (Author), Mika Hilvo (Author), Kim Ekroos (Author), Reijo Käkelä (Author), Katriina Aalto-Setälä (Author)
• Format: Book
• Published: The Company of Biologists, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocyte-like cells (HLCs) differentiated from human induced pluripotent stem cells (iPSCs) offer an alternative model to primary human hepatocytes to study lipid aberrations. However, the detailed lipid profile of HLCs is yet unknown. In the current study, functional HLCs were differentiated from...