C9ORF72-related cellular pathology in skeletal myocytes derived from ALS-patient induced pluripotent stem cells

• मुख्य लेखकों: Eileen Lynch (लेखक), Theran Semrad (लेखक), Vincent S. Belsito (लेखक), Claire FitzGibbons (लेखक), Megan Reilly (लेखक), Koji Hayakawa (लेखक), Masatoshi Suzuki (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2019-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Amyotrophic lateral sclerosis (ALS) is a late-onset neuromuscular disease with no cure and limited treatment options. Patients experience a gradual paralysis leading to death from respiratory complications on average only 2-5 years after diagnosis. There is increasing evidence that skeletal muscle i...