Selection of the First ^99mTc-Labelled Somatostatin Receptor Subtype 2 Antagonist for Clinical Translation-Preclinical Assessment of Two Optimized Candidates

• Main Authors: Melpomeni Fani (Author), Viktoria Weingaertner (Author), Petra Kolenc Peitl (Author), Rosalba Mansi (Author), Raghuvir H. Gaonkar (Author), Piotr Garnuszek (Author), Renata Mikolajczak (Author), Doroteja Novak (Author), Urban Simoncic (Author), Alicja Hubalewska-Dydejczyk (Author), Christine Rangger (Author), Piriya Kaeopookum (Author), Clemens Decristoforo (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, radiolabelled antagonists targeting somatostatin receptors subtype 2 (SST2) in neuroendocrine neoplasms demonstrated certain superior properties over agonists. Within the ERA-PerMED project "TECANT" two ^99mTc-Tetramine (N4)-derivatized SST2 antagonists (TEC...