Transient inflammation-induced ongoing pain is driven by TRPV1 sensitive afferents

• Main Authors: Mercado Ramon (Author), Ren Jiyang (Author), Eyde Nathan (Author), DeFelice Milena (Author), Okun Alec (Author), King Tamara (Author), Porreca Frank (Author)
• Format: Book
• Published: SAGE Publishing, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Tissue injury elicits both hypersensitivity to evoked stimuli and ongoing, stimulus-independent pain. We previously demonstrated that pain relief elicits reward in nerve-injured rats. This approach was used to evaluate the temporal a...