Creation of an Anti-Inflammatory, Leptin-Dependent Anti-Obesity Celastrol Mimic with Better Druggability

Obesity is characterized by an excessive body mass, but is also closely associated with metabolic syndrome. And, so far, only limited pharmacological treatments are available for obesity management. Celastrol, a pentacyclic triterpenoid from a traditional Chinese medicine (Tripterygium wilfordii Hoo...

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Main Authors: Bo Zhou (Author), Yaxia Yuan (Author), Le Shi (Author), Sheng Hu (Author), Dong Wang (Author), Yang Yang (Author), Yuanhu Pan (Author), Dexin Kong (Author), Alexander N. Shikov (Author), Pierre Duez (Author), Moonsoo Jin (Author), Xiaohua Li (Author), Xuebo Hu (Author)
Formato: Livro
Publicado em: Frontiers Media S.A., 2021-08-01T00:00:00Z.
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