Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer's Disease

• Principais autores: Akshatha Ganne (Autor), Meenakshisundaram Balasubramaniam (Autor), W. Sue T. Griffin (Autor), Robert J. Shmookler Reis (Autor), Srinivas Ayyadevara (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2022-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Glial fibrillary acidic protein (GFAP) is an intermediate filament structural protein involved in cytoskeleton assembly and integrity, expressed in high abundance in activated glial cells. GFAP is neuroprotective, as knockout mice are hypersensitive to traumatic brain injury. GFAP in cerebrospinal f...