Paraoxonase1 Genetic Polymorphisms in a Mixed Ancestry African Population

• المؤلفون الرئيسيون: M. Macharia (مؤلف), A. P. Kengne (مؤلف), D. M. Blackhurst (مؤلف), R. T. Erasmus (مؤلف), T. E. Matsha (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2014-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Paraoxonase 1 (PON1) activity is markedly influenced by coding polymorphisms, Q/R at position 192 and M/L at position 55 of the PON1 gene. We investigated the frequencies of these polymorphisms and their effects on PON1 and antioxidant activities in 844 South African mixed ancestry individuals. Geno...