Biopharmaceutical Assessment of Dexamethasone Acetate-Based Hydrogels Combining Hydroxypropyl Cyclodextrins and Polysaccharides for Ocular Delivery

• Main Authors: Roseline Mazet (Author), Xurxo García-Otero (Author), Luc Choisnard (Author), Denis Wouessidjewe (Author), Vincent Verdoot (Author), Frédéric Bossard (Author), Victoria Díaz-Tomé (Author), Véronique Blanc-Marquis (Author), Francisco-Javier (Author), Anxo Fernandez-Ferreiro (Author), Annabelle Gèze (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously developed two optimized formulations of dexamethasone acetate (DXMa) hydrogels by means of special cubic mixture designs for topical ocular administration. These gels were elaborated with hydroxypropyl-β-CD (HPβCD) and hydroxypropyl-γ-CD (HPγCD) and commercial hydrogels in order to enh...