Comprehensive genomic characterization of breast tumors with BRCA1 and BRCA2 mutations

• Main Authors: Avantika Lal (Author), Daniele Ramazzotti (Author), Ziming Weng (Author), Keli Liu (Author), James M. Ford (Author), Arend Sidow (Author)
• Format: Book
• Published: BMC, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Germline mutations in the BRCA1 and BRCA2 genes predispose carriers to breast and ovarian cancer, and there remains a need to identify the specific genomic mechanisms by which cancer evolves in these patients. Here we present a systematic genomic analysis of breast tumors with BR...