In situ monitoring of the structural change of microemulsions in simulated gastrointestinal conditions by SAXS and FRET

• Main Authors: Xia Lv (Author), Shuguang Zhang (Author), Huipeng Ma (Author), Peipei Dong (Author), Xiaodong Ma (Author), Ming Xu (Author), Yan Tian (Author), Zeyao Tang (Author), Jinyong Peng (Author), Haibo Chen (Author), Jianbin Zhang (Author)
• Format: Book
• Published: Elsevier, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microemulsions are promising drug delivery systems for the oral administration of poorly water-soluble drugs. However, the evolution of microemulsions in the gastrointestinal tract is still poorly characterized, especially the structural change of microemulsions under the effect of lipase and mucus....