Targeting slug-mediated non-canonical activation of c-Met to overcome chemo-resistance in metastatic ovarian cancer cells

• Main Authors: Linlin Chang (Author), Yan Hu (Author), Yingying Fu (Author), Tianyi Zhou (Author), Jun You (Author), Jiamin Du (Author), Lin Zheng (Author), Ji Cao (Author), Meidan Ying (Author), Xiaoyang Dai (Author), Dan Su (Author), Qiaojun He (Author), Hong Zhu (Author), Bo Yang (Author)
• Format: Book
• Published: Elsevier, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metastasis-associated drug resistance accounts for high mortality in ovarian cancer and remains to be a major barrier for effective treatment. In this study, SKOV3/T4, a metastatic subpopulation of ovarian cancer SKOV3 cells, was enriched to explore potential interventions against metastatic-associa...