Melatonin Reduces Inflammatory Injury Through Inhibiting NF-κB Activation in Rats With Colitis

• Main Authors: Jun-Hua Li (Author), Jie-Ping Yu (Author), Hong-Gang Yu (Author), Xi-Ming Xu (Author), Liang-Liang Yu (Author), Jin Liu (Author), He-Sheng Luo (Author)
• Format: Book
• Published: Hindawi Limited, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Proinflammatory mediators are important in the pathogenesis of IBD, which are regulated by activation of NF-κB. The aim of this study was to investigate whether melatonin reduces inflammatory injury and inhibits proinflammatory molecule and NF-κB in rats with colitis. Rat colitis model was establish...