Inhibition of cAMP-activated intestinal chloride secretion by diclofenac: cellular mechanism and potential application in cholera.

Cyclic AMP-activated intestinal Cl- secretion plays an important role in pathogenesis of cholera. This study aimed to investigate the effect of diclofenac on cAMP-activated Cl- secretion, its underlying mechanisms, and possible application in the treatment of cholera. Diclofenac inhibited cAMP-activ...

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Hlavní autoři: Pawin Pongkorpsakol (Autor), Nutthapoom Pathomthongtaweechai (Autor), Potjanee Srimanote (Autor), Sunhapas Soodvilai (Autor), Varanuj Chatsudthipong (Autor), Chatchai Muanprasat (Autor)
Médium: Kniha
Vydáno: Public Library of Science (PLoS), 2014-09-01T00:00:00Z.
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