Anticarin-β shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis

• প্রধান লেখক: Gan Wang (লেখক), Min Zhang (লেখক), Ping Meng (লেখক), Chengbo Long (লেখক), Xiaodong Luo (লেখক), Xingwei Yang (লেখক), Yunfei Wang (লেখক), Zhiye Zhang (লেখক), James Mwangi (লেখক), Peter Muiruri Kamau (লেখক), Zhi Dai (লেখক), Zunfu Ke (লেখক), Yi Zhang (লেখক), Wenlin Chen (লেখক), Xudong Zhao (লেখক), Fei Ge (লেখক), Qiumin Lv (লেখক), Mingqiang Rong (লেখক), Dongsheng Li (লেখক), Yang Jin (লেখক), Xia Sheng (লেখক), Ren Lai (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2022-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Unlike healthy, non-transformed cells, the proteostasis network of cancer cells is taxed to produce proteins involved in tumor development. Cancer cells have a higher dependency on molecular chaperones to maintain proteostasis. The chaperonin T-complex protein ring complex (TRiC) contains eight para...