Therapeutic potential of EVs loaded with CB2 receptor agonist in spinal cord injury via the Nrf2/HO-1 pathway

• Main Authors: Imran Ibrahim Shaikh (Author), Ramesh Bhandari (Author), Shekhar Singh (Author), Xu Zhu (Author), Khawar Ali Shahzad (Author), Chuxiao Shao (Author), Liming Cheng (Author), Jian Xiao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Spinal cord injury (SCI) poses a challenge due to limited treatment options. Recently, the effect and mechanism of Exo-loaded cannabinoid receptor type 2 (CB2) agonist AM1241(Exo + AM1241) have been applied in other inflammatory diseases but not in SCI.Methods The SCI model was set up usi...