Design of a Gene Panel to Expose the Versatile Role of Hepatic Stellate Cells in Human Liver Fibrosis

• Main Authors: Fransien van Dijk (Author), Christa M. Hazelhoff (Author), Eduard Post (Author), Gerian G. H. Prins (Author), Krista Rombouts (Author), Klaas Poelstra (Author), Peter Olinga (Author), Leonie Beljaars (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pivotal cell involved in the pathogenesis of liver fibrosis, i.e., the activated hepatic stellate cell (HSC), has a wide range of activities during the initiation, progression and even regression of the disease. These HSC-related activities encompass cellular activation, matrix synthesis and deg...