Design of a Gene Panel to Expose the Versatile Role of Hepatic Stellate Cells in Human Liver Fibrosis

• Prif Awduron: Fransien van Dijk (Awdur), Christa M. Hazelhoff (Awdur), Eduard Post (Awdur), Gerian G. H. Prins (Awdur), Krista Rombouts (Awdur), Klaas Poelstra (Awdur), Peter Olinga (Awdur), Leonie Beljaars (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2020-03-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The pivotal cell involved in the pathogenesis of liver fibrosis, i.e., the activated hepatic stellate cell (HSC), has a wide range of activities during the initiation, progression and even regression of the disease. These HSC-related activities encompass cellular activation, matrix synthesis and deg...