Therapeutic mechanism of baicalein in peritoneal dialysis-associated peritoneal fibrosis based on network pharmacology and experimental validation

• Main Authors: Xiaohui Lu (Author), Kefei Wu (Author), Simin Jiang (Author), Yi Li (Author), Yating Wang (Author), Hongyu Li (Author), Guanglan Li (Author), Qinghua Liu (Author), Yi Zhou (Author), Wei Chen (Author), Haiping Mao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Baicalein (5,6,7-trihydroxyflavone) is a traditional Chinese medicine with multiple pharmacological and biological activities including anti-inflammatory and anti-fibrotic effects. However, whether baicalein has a therapeutic impact on peritoneal fibrosis has not been reported yet. In the present st...