Intestinal Ischemia-Reperfusion Suppresses Biliary Excretion of Hepatic Organic Anion Transporting Polypeptides Substrate

• Main Authors: Hajime Maruyama (Author), Jiro Ogura (Author), Asuka Fujikawa (Author), Yusuke Terada (Author), Takashi Tsujimoto (Author), Takahiro Koizumi (Author), Kaori Kuwayama (Author), Masaki Kobayashi (Author), Hiroaki Yamaguchi (Author), Ken Iseki (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. Intestinal ischemia-reperfusion (I/R) causes gut dysfunction and promotes multi-organ failure. The liver and kidney can be affected by multi-organ failure after intestinal I/R. Organic anion transporting polypeptides (OATPs) and organic anion transporters (OATs) are recognized in a broad sp...