Integrated role of human thymic stromal cells in hematopoietic stem cell extravasation

• প্রধান লেখক: Sara A. Watson (লেখক), Yousef Javanmardi (লেখক), Luca Zanieri (লেখক), Somayeh Shahreza (লেখক), Roberta Ragazzini (লেখক), Paola Bonfanti (লেখক), Emad Moeendarbary (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2023-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract The human thymus is the site of T‐cell maturation and induction of central tolerance. Hematopoietic stem cell (HSC)‐derived progenitors are recruited to the thymus from the fetal liver during early prenatal development and from bone marrow at later stages and postnatal life. The mechanism b...