Integrated role of human thymic stromal cells in hematopoietic stem cell extravasation

• Main Authors: Sara A. Watson (Author), Yousef Javanmardi (Author), Luca Zanieri (Author), Somayeh Shahreza (Author), Roberta Ragazzini (Author), Paola Bonfanti (Author), Emad Moeendarbary (Author)
• Format: Book
• Published: Wiley, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The human thymus is the site of T‐cell maturation and induction of central tolerance. Hematopoietic stem cell (HSC)‐derived progenitors are recruited to the thymus from the fetal liver during early prenatal development and from bone marrow at later stages and postnatal life. The mechanism b...