Design, Synthesis, and Neuroprotective Activity of Phenoxyindole Derivatives on Antiamyloid Beta (Aβ) Aggregation, Antiacetylcholinesterase, and Antioxidant Activities

• Main Authors: Somjate Laivut (Author), Primchanien Moongkarndi (Author), Worawan Kitphati (Author), Pattarawit Rukthong (Author), Korbtham Sathirakul (Author), Kittisak Sripha (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this investigation, a number of phenoxyindole derivatives were designed, synthesized, and tested for their neuroprotective ability on SK-N-SH cells against Aβ₄₂-induced cell death and biologically specific activities involved in anti-Aβ aggregation, anti-AChE, and antioxida...