Advanced multi-scale mechanobiological simulations enable the distinction between healthy and pathological bone growth patterns

• 主要な著者: Willi Koller (著者), Andreas Kranzl (著者), Gabriel Mindler (著者), Arnold Baca (著者), Hans Kainz (著者)
• フォーマット: 図書
• 出版事項: Bern Open Publishing, 2024-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction & Purpose Bones adapt its shape and strength in response to mechanical loading. Tissue-level mechanical stresses, i.e., hydrostatic compressive stress and octahedral shear stress, regulate biological events on the cellular and molecular level, and thereby impact tissue histomorpholo...