Itraconazole Nanosuspensions via Dual Centrifugation Media Milling: Impact of Formulation and Process Parameters on Particle Size and Solid-State Conversion as Well as Storage Stability

Nanocrystal suspensions proved to be a potent enabling principle for biopharmaceutics classification system class II drugs with dissolution limited bioavailability. In the example of itraconazole (ITZ) as a model drug combined with electrosteric stabilization using hydroxypropyl cellulose (HPC-SL),...

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Bibliographic Details
Main Authors: Ann-Cathrin Willmann (Author), Kai Berkenfeld (Author), Thilo Faber (Author), Herbert Wachtel (Author), Georg Boeck (Author), Karl G. Wagner (Author)
Format: Book
Published: MDPI AG, 2022-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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