Analgesic and Anti-Inflammatory Effects of Perampanel in Acute and Chronic Pain Models in Mice: Interaction With the Cannabinergic System

• Main Authors: Carmen De Caro (Author), Claudia Cristiano (Author), Carmen Avagliano (Author), Mariarosaria Cuozzo (Author), Giovanna La Rana (Author), Gabriella Aviello (Author), Giovambattista De Sarro (Author), Antonio Calignano (Author), Emilio Russo (Author), Roberto Russo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pain conditions, such as neuropathic pain (NP) and persistent inflammatory pain are therapeutically difficult to manage. Previous studies have shown the involvement of glutamate receptor in pain modulation and in particular same of these showed the key role of the AMPA ionotropic glutamate receptor...