Metastable Reprogramming State of Single Transcription Factor-Derived Induced Hepatocyte-Like Cells

• Váldodahkkit: Seon In Hwang (Dahkki), Tae Hwan Kwak (Dahkki), Ji Hyun Kang (Dahkki), Jonghun Kim (Dahkki), Hyunseong Lee (Dahkki), Kee-Pyo Kim (Dahkki), Kinarm Ko (Dahkki), Hans R. Schöler (Dahkki), Dong Wook Han (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2019-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

We previously described the generation of induced hepatocyte-like cells (iHeps) using the hepatic transcription factor Hnf1a together with small molecules. These iHeps represent a hepatic state that is more mature compared with iHeps generated with multiple hepatic factors. However, the underlying m...