Comparative proteomic analyses of Duchenne muscular dystrophy and Becker muscular dystrophy muscles: changes contributing to preserve muscle function in Becker muscular dystrophy patients

• Main Authors: Daniele Capitanio (Author), Manuela Moriggi (Author), Enrica Torretta (Author), Pietro Barbacini (Author), Sara De Palma (Author), Agnese Viganò (Author), Hanns Lochmüller (Author), Francesco Muntoni (Author), Alessandra Ferlini (Author), Marina Mora (Author), Cecilia Gelfi (Author)
• Format: Book
• Published: Wiley, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are characterized by muscle wasting leading to loss of ambulation in the first or third decade, respectively. In DMD, the lack of dystrophin hampers connections between intracellular cytoskeleton and cell membr...