Coumarins effectively inhibit bacterial α-carbonic anhydrases

Coumarins are known to act as prodrug inhibitors of mammalian α-carbonic anhydrases (CAs, EC 4.2.1.1) but they were not yet investigated for the inhibition of bacterial α-CAs. Here we demonstrate that such enzymes from the bacterial pathogens Neisseria gonorrhoeae (NgCAα) and Vibrio cholerae (VchCAα...

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Bibliographic Details
Main Authors: Simone Giovannuzzi (Author), Chad S. Hewitt (Author), Alessio Nocentini (Author), Clemente Capasso (Author), Daniel P. Flaherty (Author), Claudiu T. Supuran (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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