Decreased TLR4 expression on monocytes may cause regulatory T cells abnormality in patients with primary immune thrombocytopenia

• मुख्य लेखकों: Yating Hao (लेखक), Huiyuan Li (लेखक), Yang Li (लेखक), Mingen Lyu (लेखक), Donglei Zhang (लेखक), Rongfeng Fu (लेखक), Yue Guan (लेखक), Shixuan Wang (लेखक), Boyang Sun (लेखक), Xueqing Dou (लेखक), Renchi Yang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2017-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Primary immune thrombocytopenia (ITP) is an autoimmune disease with many immune dysfunctions including T helper type 1 cell (Th1) polarization and regulatory T cells (Tregs) deficiency. This study aimed to determine the effects of TLR4 on Treg differentiation and the cytokine production of periphera...