Successful treatment of acute B lymphoblastic leukemia relapse in the skin and testicle by anti-CD19 CAR-T with IL-6 knocking down: a case report

• Main Authors: Ze-Fa Liu (Author), Li-Yun Chen (Author), Jin Wang (Author), Li-qing Kang (Author), Hua Tang (Author), Yao Zhou (Author), Hai-Xia Zhou (Author), Ai-Ning Sun (Author), De-Pei Wu (Author), Sheng-Li Xue (Author)
• Format: Book
• Published: BMC, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Extramedullary relapse is an important cause of treatment failure among patients with acute lymphoblastic leukemia (ALL). This type of relapse is commonly observed in the central nervous system, while it is rare in the testicles and skin. Chimeric antigen receptor-modified T cell...